The broad spectrum host-directed agent ivermectin as an antiviral for SARS-CoV-2 ? (2021)
"... It was initially shown to inhibit nuclear import not only of IN, but also of simian virus SV40 large tumour antigen (T-ag) and other IMPĪ±/Ī²1- (but not IMPĪ²1-) dependent cargoes, consistent with the idea that IMPĪ± (not IN) is the direct target of ivermectin [34,35]. Subsequent work has confirmed this, with ivermectinās ability to inhibit the nuclear accumulation of various different host, including NF-kB p65 [37,38] and viral proteins demonstrated in transfected and infected cell systems (see Table 1) [14,34]. Ivermectinās ability to inhibit binding of IMPĪ± to the viral proteins NS5 and T-ag has also been confirmed in a cellular context using the biomolecular fluorescence complementation technique [11] (Table 1)."
Why the FDA and the VRBPAC did not ask the CTGTAC for their assessment of the risks of mRNA 'vaccines' like they did for the AAV vaccines is a question that needs answering.
Thank you so much for all of your voluminous, stellar research to help cancer patients!!!
Of course, it is hugely difficult for the likes of me to understand this material, but I am going to to read and re-read it.
I am definitely going to share this material with my breast cancer group, and with other people who have cancer. Years ago, when my uncle, a doctor, died of lymphoma, my aunt was convinced that his polio shots had been the causative agents. She even used his library card at the med school's library, to do some research.
Thanks for this complex Saturday morning read. I canāt tell you how much I appreciate you putting this together. When my finances are a little more secure you are on my upgrade list.
IVM helps stop TAG going into the nucleus:
The broad spectrum host-directed agent ivermectin as an antiviral for SARS-CoV-2 ? (2021)
"... It was initially shown to inhibit nuclear import not only of IN, but also of simian virus SV40 large tumour antigen (T-ag) and other IMPĪ±/Ī²1- (but not IMPĪ²1-) dependent cargoes, consistent with the idea that IMPĪ± (not IN) is the direct target of ivermectin [34,35]. Subsequent work has confirmed this, with ivermectinās ability to inhibit the nuclear accumulation of various different host, including NF-kB p65 [37,38] and viral proteins demonstrated in transfected and infected cell systems (see Table 1) [14,34]. Ivermectinās ability to inhibit binding of IMPĪ± to the viral proteins NS5 and T-ag has also been confirmed in a cellular context using the biomolecular fluorescence complementation technique [11] (Table 1)."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577703/
Have you had a chance to read and analyze this? Do you know anyone best suited to describe the impact of this study? Note the sponsors: NIH.
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiae031/7625543?login=false#443509963
Cyprinus carpio, another capolavoro.
Why the FDA and the VRBPAC did not ask the CTGTAC for their assessment of the risks of mRNA 'vaccines' like they did for the AAV vaccines is a question that needs answering.
Apparently it was too hard for either Pfizer or Moderna to find a backronym for "HUBRIS."
Thank you so much for all of your voluminous, stellar research to help cancer patients!!!
Of course, it is hugely difficult for the likes of me to understand this material, but I am going to to read and re-read it.
I am definitely going to share this material with my breast cancer group, and with other people who have cancer. Years ago, when my uncle, a doctor, died of lymphoma, my aunt was convinced that his polio shots had been the causative agents. She even used his library card at the med school's library, to do some research.
Thanks again!!
Thanks for this complex Saturday morning read. I canāt tell you how much I appreciate you putting this together. When my finances are a little more secure you are on my upgrade list.
Just say no.