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Not saying there is an autoimmune component to long covid but I find it interesting that the common symptoms you listed for Long Covid are the same ones I experienced leading up to my diagnosis with a very rare autoimmune disease that has no biomarker (ie: there are no blood tests that can diagnose it like many other AI diseases). There is a misconception that all autoimmune diseases can be detected by AI specific blood tests, blood abnormalities, etc but this is not the case. It makes you wonder if there is an autoimmune process going on in at least some of the people experiencing Long Covid. But I will concede that I suspect a number are experiencing post viral fatigue which is not uncommon after viral infections such as Mono, etc. It can take 6 months to recover from it. I knew quite a few kids when I was young who went thru it.
Thank you for your comments, have to fully agree it's likely a significant contributor and like many autoimmune disorders may be very difficult to diagnose, often by elimination.
The last section of this paper discusses the subject.
Long COVID: to investigate immunological mechanisms and sex/gender related aspects as fundamental steps for tailored therapy
My specific AI disease is diagnosed by symptoms only. In my case the disease had to get much worse before doctors could figure out what was going on, during the 4 years leading up to my diagnosis I just had severe general symptoms such as those you listed in your post, the fatigue was so severe as to be disabling. But since my blood work looked fine doctors would either admit they had no idea why I felt so horrible or thought it was in my head. Once I was finally diagnosed and was started on prednisone and various immune suppressants I started to immediately improve.
I will add that you have to be careful when looking at autoantibodies as abnormal results are actually normal in a % of the healthy population. A number of researchers have fallen into this trap while studying Chronic Fatigue Syndrome. More often than not in CFS research the supposedly abnormal autoantibodies detected aren't anything to get excited about.
Copy of a reply I posted last week. General advice is try to avoid long term use of corticosteroids as this can lead to cardiovascular disease & osteoporosis. CBD, D & Glucosamine are natural immune regulators and ok long term:
Long covid
@martin17773 @m @ShemNehm
I bookmarked this last May in case it might help someone. I would also add Resveratrol via red wine & black grapes (Malbec, Cabernet Sauvignon, Merlot), an antioxidant rich diet and IVM or HCQ, quercetin to clear any remnant RNA spike sources. HCQ helps neurological issues too, + glucosamine as an anti cancer agent and to reduce elevated inflammatory cytokine levels. As ever this is not medical advice, you will need to check for suitability for you, dosing and for interactions via a licensed medical professional who knows your medical history.
@m Vaccine Injury: Long COVID and inflammatory vaccine reaction share the same cause Spike Protein. People are going to need to know about natural remedies. This thread will offer some papers with advice. First luteolin.
Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue
Not saying there is an autoimmune component to long covid but I find it interesting that the common symptoms you listed for Long Covid are the same ones I experienced leading up to my diagnosis with a very rare autoimmune disease that has no biomarker (ie: there are no blood tests that can diagnose it like many other AI diseases). There is a misconception that all autoimmune diseases can be detected by AI specific blood tests, blood abnormalities, etc but this is not the case. It makes you wonder if there is an autoimmune process going on in at least some of the people experiencing Long Covid. But I will concede that I suspect a number are experiencing post viral fatigue which is not uncommon after viral infections such as Mono, etc. It can take 6 months to recover from it. I knew quite a few kids when I was young who went thru it.
Thank you for your comments, have to fully agree it's likely a significant contributor and like many autoimmune disorders may be very difficult to diagnose, often by elimination.
The last section of this paper discusses the subject.
Long COVID: to investigate immunological mechanisms and sex/gender related aspects as fundamental steps for tailored therapy
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8462012/
My specific AI disease is diagnosed by symptoms only. In my case the disease had to get much worse before doctors could figure out what was going on, during the 4 years leading up to my diagnosis I just had severe general symptoms such as those you listed in your post, the fatigue was so severe as to be disabling. But since my blood work looked fine doctors would either admit they had no idea why I felt so horrible or thought it was in my head. Once I was finally diagnosed and was started on prednisone and various immune suppressants I started to immediately improve.
I will add that you have to be careful when looking at autoantibodies as abnormal results are actually normal in a % of the healthy population. A number of researchers have fallen into this trap while studying Chronic Fatigue Syndrome. More often than not in CFS research the supposedly abnormal autoantibodies detected aren't anything to get excited about.
Copy of a reply I posted last week. General advice is try to avoid long term use of corticosteroids as this can lead to cardiovascular disease & osteoporosis. CBD, D & Glucosamine are natural immune regulators and ok long term:
Long covid
@martin17773 @m @ShemNehm
I bookmarked this last May in case it might help someone. I would also add Resveratrol via red wine & black grapes (Malbec, Cabernet Sauvignon, Merlot), an antioxidant rich diet and IVM or HCQ, quercetin to clear any remnant RNA spike sources. HCQ helps neurological issues too, + glucosamine as an anti cancer agent and to reduce elevated inflammatory cytokine levels. As ever this is not medical advice, you will need to check for suitability for you, dosing and for interactions via a licensed medical professional who knows your medical history.
@m Vaccine Injury: Long COVID and inflammatory vaccine reaction share the same cause Spike Protein. People are going to need to know about natural remedies. This thread will offer some papers with advice. First luteolin.
Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue
https://t.co/Vzr34PWQtY
Next, zinc
Zinc supplementation and immune factors in adults: a systematic review and meta-analysis of randomized clinical trials
https://t.co/ReTcZixsyC
Let's look at olive leaf extract as an anti-inflammatory that fits the damage profile.
Olive Leaf Extract Attenuates Inflammatory Activation and DNA Damage in Human Arterial Endothelial Cells
https://t.co/nVD6LXr0OJ