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I'm helping a team collect data from public obituaries. Mindblowing. Babies, children, teens, young adults, adults (forget age 70+, even). Sudden passings, unexpected passings, in-the-night passings, sudden/aggressive cancers...
One of the articles above mentions: "cross-linked interstitial and perivascular matrix may be highly resistant to proteases. Matrix cross-linking enzymes, such as lysyl oxidases (13) and transglutaminase-2 (14), are markedly induced in remodeling and failing hearts, and may cause formation of irreversible fibrotic foci (Figure 1B)."
This is interesting in relation to Vojdani and Kharrazian (2020): "Looking at the reaction between SARS-CoV-2 spike protein antibody and tissue proteins (Fig. 1A), we found that the strongest reactions were with transglutaminase 3 (tTG3), transglutaminase 2 (tTG2), ENA, myelin basic protein (MBP), mitochondria, nuclear antigen (NA), Ī±-myosin, thyroid peroxidase (TPO), collagen, claudin 5+6, and S100B."
Vojdani A, Kharrazian D. Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases. Clin Immunol. 2020 Aug;217:108480. doi: 10.1016/j.clim.2020.108480.
So could that mean that there is a transglutaminase-2-similar motif in Spike, similar enough to trigger autoantibodies against the real transglutaminase 2, and similar enough to form irreversible cross-linking in the giant fibrous clots that are being found?
I'm helping a team collect data from public obituaries. Mindblowing. Babies, children, teens, young adults, adults (forget age 70+, even). Sudden passings, unexpected passings, in-the-night passings, sudden/aggressive cancers...
Interesting post as always, thank you.
One of the articles above mentions: "cross-linked interstitial and perivascular matrix may be highly resistant to proteases. Matrix cross-linking enzymes, such as lysyl oxidases (13) and transglutaminase-2 (14), are markedly induced in remodeling and failing hearts, and may cause formation of irreversible fibrotic foci (Figure 1B)."
This is interesting in relation to Vojdani and Kharrazian (2020): "Looking at the reaction between SARS-CoV-2 spike protein antibody and tissue proteins (Fig. 1A), we found that the strongest reactions were with transglutaminase 3 (tTG3), transglutaminase 2 (tTG2), ENA, myelin basic protein (MBP), mitochondria, nuclear antigen (NA), Ī±-myosin, thyroid peroxidase (TPO), collagen, claudin 5+6, and S100B."
Vojdani A, Kharrazian D. Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases. Clin Immunol. 2020 Aug;217:108480. doi: 10.1016/j.clim.2020.108480.
So could that mean that there is a transglutaminase-2-similar motif in Spike, similar enough to trigger autoantibodies against the real transglutaminase 2, and similar enough to form irreversible cross-linking in the giant fibrous clots that are being found?