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Unless I am misunderstanding: Between the post-vax autoimmune manifestations described in this article and Walter Chesnut's SPED hypothesis (url below), it would seem that the vascular system of the "vaccinated", and those who had COVID-19, is under attack from two different/deadly angles.
Thanks for the link. As with immunosuppression and tumorigenesis these aren't mutually exclusive pathways and I've found up to 30 so far, there are more when you get inside the nucleus.
Your vasculature is under attack in multiple ways, including ACE2 binding & RAS disruption, autoimmune attack against other targets, microcilia disruption and so on.
I am again amazed because you had to read and understand shite loads of papers and sources, then organize, draft, edit edit edit, probably reread and refer back to the materials, repeat, repeat and keep at it until you had as succinct an essay as possible that is also thorough enough, that your readers can understand. You are going to have a very nice treatise! Thank you for this. Wow.
Thank you, the hardest part is cutting out some material or it would be huge and impenetrable! I've also added some photos of typical clinical presentations, need to keep in mind this is a reference for practicing physicians too.
Great research and deep dive. Dr. Bruce Patterson has research along the same lines, but using the monocyte model of pathology. He recommends statins to reduce the glycocalyx damage and reduce adhesion. Early diagnosis and treatment is vital to any resolution, and perhaps proteolytic enzymes like Nattokinase and steroids to reduce inflammation. It is notable that people with PASC have low cortisol levels that control the release of ACTH and CRH. You shine a light into dark corners and will save lives.
Thank you for your kind words and stressing the importance of early diagnosis with immune suppression and spike protein clearance combined, and how those with LC may have hypocortisolism, which will contribute to all manner of symptoms.
Hypoxia also seems involved. Vasculitis was one of the first topics I blogged about, because the symptoms sounded like mine at the time. Endocannabinoid deficiency or imbalance can be involved. Low magnesium, low methyl Bs. I had adrenal fatigue symptoms then.
With microvascular rarefaction then oxygen carrying capacity is compromised, the Warburg effect and kynurenine pathway pathologies may be invoked. It can soon get complicated as destructive feedback loops establish.
Spike protein (inc vax) induced immunodeficiency & carcinogenesis megathread #29: The tryptophan catabolite or kynurenine pathway and long COVID
Unless I am misunderstanding: Between the post-vax autoimmune manifestations described in this article and Walter Chesnut's SPED hypothesis (url below), it would seem that the vascular system of the "vaccinated", and those who had COVID-19, is under attack from two different/deadly angles.
https://wmcresearch.substack.com/p/update-spike-protein-endothelial
Thanks for the link. As with immunosuppression and tumorigenesis these aren't mutually exclusive pathways and I've found up to 30 so far, there are more when you get inside the nucleus.
Your vasculature is under attack in multiple ways, including ACE2 binding & RAS disruption, autoimmune attack against other targets, microcilia disruption and so on.
I am again amazed because you had to read and understand shite loads of papers and sources, then organize, draft, edit edit edit, probably reread and refer back to the materials, repeat, repeat and keep at it until you had as succinct an essay as possible that is also thorough enough, that your readers can understand. You are going to have a very nice treatise! Thank you for this. Wow.
Thank you, the hardest part is cutting out some material or it would be huge and impenetrable! I've also added some photos of typical clinical presentations, need to keep in mind this is a reference for practicing physicians too.
The photos are important! Very helpful.
I would have a difficult time cutting material out!
The art and science of editing~
I don't speak the language, but I believe I have an idea of what's going on here. Thanks!
Great research and deep dive. Dr. Bruce Patterson has research along the same lines, but using the monocyte model of pathology. He recommends statins to reduce the glycocalyx damage and reduce adhesion. Early diagnosis and treatment is vital to any resolution, and perhaps proteolytic enzymes like Nattokinase and steroids to reduce inflammation. It is notable that people with PASC have low cortisol levels that control the release of ACTH and CRH. You shine a light into dark corners and will save lives.
Thank you for your kind words and stressing the importance of early diagnosis with immune suppression and spike protein clearance combined, and how those with LC may have hypocortisolism, which will contribute to all manner of symptoms.
Hypoxia also seems involved. Vasculitis was one of the first topics I blogged about, because the symptoms sounded like mine at the time. Endocannabinoid deficiency or imbalance can be involved. Low magnesium, low methyl Bs. I had adrenal fatigue symptoms then.
With microvascular rarefaction then oxygen carrying capacity is compromised, the Warburg effect and kynurenine pathway pathologies may be invoked. It can soon get complicated as destructive feedback loops establish.
Spike protein (inc vax) induced immunodeficiency & carcinogenesis megathread #29: The tryptophan catabolite or kynurenine pathway and long COVID
https://doorlesscarp953.substack.com/p/spike-protein-inc-vax-induced-immunodeficiency-d03